Acabrunat 100mg contains Acalabrutinib, a Bruton’s tyrosine kinase (BTK) inhibitor, primarily used in the treatment of certain types of blood cancers, such as chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL)

Brand Name: Acabrunat

Composition: Acalabrutinib

Mechanism of Action:

By specifically inhibiting Bruton's tyrosine kinase (BTK), acalabrutinib disrupts signaling pathways that support the proliferation and survival of B-cell malignancies. It assists in reducing or halting the proliferation of malignant cells by blocking BTK.

Uses:

• Chronic Lymphocytic Leukemia
• Mantle Cell Lymphoma (in patients who have received at least one prior therapy)

Dosage and Administration:

The usual recommended dose is 100 mg taken twice daily. Swallow the capsules whole with water, and do not open, break, or chew them.

Side Effects:

• Headache
• Fatigue
• Diarrhea
• Musculoskeletal pain.
• Increased risk of infections
• Bleeding problems
• Heart rhythm disturbances.

Safety Advise:

Heart  

Irregular heart rhythms may be brought on by acalabrutinib, especially in individuals who already have cardiac issues. Kindly speak with your healthcare provider.

Liver  

Liver function should be monitored regularly, as Acalabrutinib can cause abnormalities in liver. Kindly speak with your healthcare provider.

Kidney  

Kidney function should be monitored regularly, as Acalabrutinib can cause abnormalities in kidney. Kindly speak with your healthcare provider.

Pregnancy  

Acalabrutinib should not be used while pregnant due to the potential harm it can cause to the fetus. Kindly speak with your healthcare provider.

Breastfeeding  

When using this drug, it is not advised. If you are or will be breastfeeding, Kindly speak with your healthcare provider.

Driving  

Acabrunat may make you tired or dizzy. Till you understand how the medicine affects you. Kindly speak with your healthcare provider.

Storage:

Store Acabrunat at room temperature, away from moisture and heat.

How to use this Medication?

Swallow the capsules whole while taking Acabrunat, along with a full glass of water. Pay close attention to what your doctor tells you, and never alter or stop taking a medication without first talking to your doctor.

This drug should not be taken with grapefruit juice. After taking this drug for two hours, avoid consuming antacids and H2-blockers.

Talk to your care team about the use of this medication in children. Special care may be needed.

Disclaimer:

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